Allery Treatment News

ZYTIGA Phase 3 Study Results Re Metastatic Castration-Resistant Prostate Cancer

June 01, 2017

A study titled "Abiraterone and Increased Survival in Metastatic Prostate Cancer," published in the May 26 issue of NEJM, found that patients with metastatic castration-resistant prostate cancer who have received prior chemotherapy containing docetaxel showed a significant improvement in overall survival when treated with ZYTIGA™ (abiraterone acetate) plus prednisone compared to patients treated with prednisone plus placebo. The COU-AA-301 study was sponsored by Ortho Biotech Oncology Research & Development, unit of Cougar Biotechnology, Inc.

Results of the pivotal Phase 3, randomized, placebo-controlled, multicenter study showed that at pre-specified interim analysis, treatment with ZYTIGA in combination with prednisone resulted in a 35.4 percent reduction in the risk of death (14.8 months vs. 10.9 months [hazard ratio (HR) = 0.65; 95 percent CI: 0.54, 0.77; p